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Permanent discontinuation of Modecate (fluphenazine decanoate) injection by end of December 2018 Posted on 23 Jan 2018

An advanced notification of the permanent discontinuation of Modecate (Fluphenazine decanoate) injection. Production will cease in mid-2018, and the product is expected to remain available in the UK up until the end of 2018. All presentations will be withdrawn (Modecate 25mg/ml and Modecate concentrate injection 100mg/ml).

We have been advised that the discontinuation is due to the unpredictability of the supply of fluphenazine decanoate from the third party manufacturer in South Africa. The discontinuation is not due to any safety issue and Modecate injection currently on the market can continue to be used.

  • No new patients should be initiated on to treatment with fluphenazine decanoate. This has been communicated to CWPT prescribers.
  • Patients currently treated with fluphenazine decanoate should be reviewed and switched to an alternative therapy. If the patient is open to CWPT this will be undertaken by CWPT services.
  • GP’s can contact the ‘GP Mental Health Advice Line’ if they require advice on switching therapy.


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